Publications

  • De Caluwé J, de Melo JRF, Tosenberger A, Hermans C, Verbruggen N, Leloup J-C, Gonze D (2017) Modeling the photoperiodic entrainment of the plant circadian clock. J Theor Biol 420: 220-231.

  • De Caluwé J, Xiao Q, Hermans C, Verbruggen N, Leloup J-C, Gonze D (2016) A compact model for the complex plant circadian clock. Front. Plant Sci. 7: 74.

  • Schmal C, Leloup J-C, and Gonze D (2014) Modeling and simulating the Arabidopsis thaliana circadian clock using XPP-AUTO. Met Mol Biol 1158, 337-58.

  • Deneubourg J-L, Destexhe A, Leloup J-C (2013) Functionality and dynamics in biological systems. Chaos, Solitons & Fractals 50, 1-2.

  • Leloup J-C, Goldbeter A (2013) Critical phase shifts slow down circadian clock recovery: Implications for jet lag. J Theor Biol 333, 47-57.

  • Goldbeter A, Gérard C, Gonze D, Leloup J-C, Dupont G (2012) Systems Biology of Cellular Rhythms. FEBS Lett 586(18), 2955-65.

  • Leloup J-C, Goldbeter A (2011) Modeling the dual role of PER phosphorylation and its effect on the period and phase of the mammalian circadian clock. IET Sys Biol 5(1), 44.

  • Goldbeter A, Gérard C, Leloup J-C (2010) Biologie des systèmes et rythmes cellulaires. Médecine/Sciences 26, 49-56.

  • Gonze D, and Leloup J-C (2009) Towards a synthetic circadian clock in mammals. Cell Sci Rev 5, 45-55.

  • Leloup J-C (2009) Circadian clocks and phosphorylation: Insights from computational modeling. Cent Eur J Biol 4, 290-303.

  • Leloup J-C and Goldbeter A (2009) Modeling the dual role of PER phosphorylation and its effect on the period and phase of the mammalian circadian clock. In : Proceedings of the Foundations of Systems Biology in Engineering, pp. 16-27.

  • Leloup J-C and Goldbeter A (2008) Modeling the circadian clock : From molecular mechanism to physiological disorders. BioEssays 30, 590-600.

  • Leloup J-C, Gonze D, and Goldbeter A (2006) Computational models for circadian rhythms : Deterministic versus stochastic approaches. In : "Computational Systems Biology", A Kriete and R Eils eds, pp. 249-291 (Elsevier Academic Press, Burlington-San Diego, USA).

  • Goldbeter A and Leloup J-C (2004) Modélisation des rythmes circadiens chez la drosophile et chez les mammifères. In : Comptes-rendus de la 7ème Rencontre du Non-Linéaire, Y Pomeau, R Ribotta eds, pp. 115-123.

  • Goldbeter A, Leloup J-C (2004) Mathematical modeling of circadian rhythms in Drosophila and mammals. In : Proceedings of the 16th International Symposium on Mathematical Theory of Networks and Systems, B De Moor, B Motmans, J Willems, P Van Dooren, V Blondel eds.

  • Goldbeter A, Gonze D, Houart G, Leloup J-C, Halloy J, Dupont G (2004) From periodic oscillations to chaos in metabolic and genetic control networks. In : Proceedings of the 16th International Symposium on Mathematical Theory of Networks and Systems, B De Moor, B Motmans, J Willems, P Van Dooren, V Blondel eds.

  • Goldbeter A, Gonze D, Houart G, Leloup J-C, Halloy J, Dupont G (2004) Periodic oscillations and chaos in cellular regulatory networks. In : Simplicity Behind Complexity (Proceedings of the 3rd European Interdisciplinary School on Nonlinear Dynamics for System and Signal Analysis, Euroattractor 2002), pp. 69-84.

  • Leloup J-C and Goldbeter A (2004) Modeling the mammalian circadian clock: Sensitivity analysis and multiplicity of oscillatory mechanisms. J Theor Biol 230, 541-562.

  • Leloup J-C and Goldbeter A (2004) Modelling the circadian clock in Drosophila and mammals. In : Modelling and simulation of biological processes in the context of genomics (Proceedings of the Evry Spring School, 2004) P Amar, J-P Comet, F Képès, V Norris eds, pp 79-86.

  • Forger DB, Dean II DA, Gurdziel K, Leloup J-C, Lee C, Von Gall C, Etchegaray J-P, Kronauer RE, Goldbeter A, Peskin CS, Jewett ME, and Weaver DR (2003) Development and validation of computational models for mammalian circadian oscillators. OMICS 7, 385-398.

  • Goldbeter A and Leloup J-C (2003) La modélisation des rythmes du vivant. Pour la Science 314, 70-76.

  • Gonze D, Halloy J, Leloup J-C, and Goldbeter A (2003) Stochastic models for circadian rhythms: Effect of molecular noise on periodic and chaotic behaviour. CR Biologies 326, 189-203.

  • Klarsfeld A, Leloup J-C, and Rouyer F (2003) Circadian rhythms of locomotor activity in Drosophila. Behav Proc 64, 161-175.

  • Leloup J-C and Goldbeter A (2003) Toward a detailed computational model for the mammalian circadian clock. Proc Natl Acad Sci USA 100, 7051-7056.

  • Leloup J-C and Goldbeter A (2001) A molecular explanation for the long-term suppression of circadian rhythms by a single light pulse. Am J Physiol Regul Integr Comp Physiol 280, R1206-R1212.

  • Goldbeter A, Gonze D, Houart G, Leloup J-C, Halloy J, and Dupont G (2001) From simple to complex oscillatory behavior in metabolic and genetic control network. Chaos 11, 247-260.

  • Leloup J-C and Goldbeter A (2000) Modeling the molecular regulatory mechanism of circadian rhytms in Drosophila. BioEssays 22, 84-93.

  • Gonze D, Leloup J-C, and Goldbeter A (2000) Theoretical models for circadian rhythms in Neurospora and Drosophila. Comptes Rendus Hebd Acad Sci (Paris) Ser III 323, 57-67.

  • Leloup J-C, Gonze D, and Goldbeter A (1999) Limit cycle models for circadian rhythms based on transcriptional regulation in Neurospora and Drosophila. J Biol Rhythms 14, 433-448.

  • Leloup J-C and Goldbeter A (1999) Chaos and birhythmicity in a model for circadian oscillations of the PER and TIM proteins in Drosophila. J Theor Biol 198, 445-459.

  • Leloup J-C and Goldbeter A (1998) A model for circadian rhythms in Drosophila incorporating the formation of a complex between the PER and TIM proteins. J Biol Rhythms 13, 70-87.

  • Leloup J-C and Goldbeter A (1998) Modeling circadian rhythms of the PER and TIM proteins in Drosophila. In: Proceedings of the International Congress of Chronobiology. Biological Clocks: Mechanisms and Applications Y. Touitou (Ed.), Elsevier, Amsterdam, pp 81-88.

  • Leloup JC and Goldbeter A (1997) Temperature compensation of circadian rhythms: Control of the period in a model for circadian oscillations of the PER protein in Drosophila. Chronobiol Int 14, 511-520.

ULB - entreprise écodynamique